I'm not sure you're aware, but since the drop rates of.. well.. EVERYTHING are hugely boosted in Ascension, it's almost impossible to do skinning profession, as you fill out your bags with trash in less than 5 minutes.
To fix this, I propose adding a custom toggle ability that, if active, would make mobs you kill give vanilla-level drops (or no drops at all). So if you're just trying to level up your LW you can get more than 10 leather without filling 40+ slots in your bags with trash loot. Not everyone got expensive utility pets to offload vendor trash.
Tacking on to this suggestion with an additional comment regarding skinning:
Since mobs scale up with your level, it can be tough to get a feel for which mobs are your next target to level (e.g. - fire whelps in Redridge require Skinning lvl 80, but in Ascension, there's no tooltip to tell you, or to give you a clue that you need to grind on lower level mobs to skill up)
Can Ascension add some form of tool tip for skinning to give clues as to what levels of mobs are really orange vs red vs green? (right now they're all red)